Patrizia Gazzerro Selected Research

Mevalonic Acid (Mevalonate)

11/2021	Towards an Improvement of Anticancer Activity of Benzyl Adenosine Analogs.
1/2021	Lipid homeostasis and mevalonate pathway in COVID-19: Basic concepts and potential therapeutic targets.
1/2020	NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity.
1/2018	N6-isopentenyladenosine dual targeting of AMPK and Rab7 prenylation inhibits melanoma growth through the impairment of autophagic flux.
10/2017	Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma.
7/2017	The isoprenoid derivative N6 -benzyladenosine CM223 exerts antitumor effects in glioma patient-derived primary cells through the mevalonate pathway.
11/2014	N6-isopentenyladenosine affects cytotoxic activity and cytokines production by IL-2 activated NK cells and exerts topical anti-inflammatory activity in mice.
3/2014	Antiangiogenic effects of N6-isopentenyladenosine, an endogenous isoprenoid end product, mediated by AMPK activation.
12/2013	N6-isopentenyladenosine, an endogenous isoprenoid end product, directly affects cytotoxic and regulatory functions of human NK cells through FDPS modulation.
3/2009	N6-isopentenyladenosine inhibits cell proliferation and induces apoptosis in a human colon cancer cell line DLD1.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Patrizia Gazzerro Research Topics

Disease

45	Neoplasms (Cancer) 01/2022 - 05/2006
10	Colorectal Neoplasms (Colorectal Cancer) 11/2021 - 07/2008
9	Colonic Neoplasms (Colon Cancer) 09/2019 - 01/2008
7	Breast Neoplasms (Breast Cancer) 11/2012 - 11/2005
6	Neoplasm Metastasis (Metastasis) 04/2020 - 05/2006
6	Glioma (Gliomas) 01/2020 - 06/2015
5	Inflammation (Inflammations) 01/2021 - 02/2009
5	Brain Neoplasms (Brain Tumor) 01/2019 - 10/2014
5	Obesity 01/2012 - 06/2007
4	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 10/2017
4	Multiple Sclerosis 06/2015 - 01/2013
2	COVID-19 01/2021 - 11/2020
2	Infections 01/2021 - 11/2020
2	Melanoma (Melanoma, Malignant) 01/2020 - 01/2018
2	Carcinogenesis 10/2018 - 09/2009
2	Dermatitis 07/2017 - 11/2014
2	Coronary Disease (Coronary Heart Disease) 10/2014 - 01/2012
2	Nervous System Diseases (Neurological Disorders) 10/2014 - 12/2013
2	Substance-Related Disorders (Drug Abuse) 01/2010 - 06/2007
2	Necrosis 09/2009 - 10/2006
1	Cytokine Release Syndrome 01/2021
1	Virus Diseases (Viral Diseases) 01/2021
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021
1	Cancer Pain 01/2020
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2017
1	Prostatic Neoplasms (Prostate Cancer) 06/2015
1	Parkinson Disease (Parkinson's Disease) 10/2014
1	Alzheimer Disease (Alzheimer's Disease) 10/2014
1	Stroke (Strokes) 10/2014
1	Central Nervous System Diseases (CNS Diseases) 10/2014
1	Hematologic Neoplasms (Hematological Malignancy) 08/2013
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2013

Drug/Important Bio-Agent (IBA)

13	CannabinoidsIBA 01/2021 - 05/2006
11	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2004
11	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 06/2015 - 11/2005
10	Mevalonic Acid (Mevalonate)IBA 11/2021 - 03/2009
10	EndocannabinoidsIBA 01/2020 - 05/2006
9	RimonabantIBA 01/2017 - 10/2006
8	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2021 - 11/2006
6	LipidsIBA 01/2021 - 11/2005
5	Terpenes (Terpenoids)IBA 06/2019 - 11/2006
5	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2012 - 11/2005
4	EnzymesIBA 11/2021 - 03/2011
4	CateninsIBA 09/2021 - 11/2012
4	Adenosine (Adenocard)FDA LinkGeneric 01/2019 - 11/2014
4	anandamide (arachidonylethanolamide)IBA 11/2012 - 11/2005
3	NucleosidesIBA 01/2022 - 03/2009
3	CholesterolIBA 01/2021 - 01/2012
3	Pharmaceutical PreparationsIBA 01/2020 - 03/2012
3	Biological ProductsIBA 01/2017 - 05/2008
3	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2016 - 01/2010
3	CB2 Cannabinoid ReceptorIBA 06/2015 - 01/2013
2	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2019
2	farnesyl pyrophosphate (farnesyl diphosphate)IBA 11/2021 - 07/2017
2	Oxidoreductases (Dehydrogenase)IBA 01/2021 - 06/2010
2	Protein Isoforms (Isoforms)IBA 01/2020 - 10/2018
2	Fluorouracil (Carac)FDA LinkGeneric 09/2019 - 01/2016
2	LigandsIBA 01/2018 - 01/2012
2	Croton OilIBA 07/2017 - 11/2014
2	TubulinIBA 01/2016 - 08/2013
2	Estrogens (Estrogen)FDA Link 03/2012 - 01/2008
2	2-methyl-2'-F-anandamideIBA 06/2010 - 05/2007
2	Lovastatin (Mevacor)FDA LinkGeneric 12/2008 - 11/2006
1	MethyltransferasesIBA 01/2022
1	Temozolomide (Temodar)FDA LinkGeneric 01/2022
1	Positive Regulatory Domain I-Binding Factor 1IBA 11/2021
1	alpha-Crystallin B ChainIBA 05/2021
1	Small Heat-Shock ProteinsIBA 05/2021
1	nutlin 3IBA 01/2020
1	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2020
1	Tumor Suppressor Protein p14ARF (p14ARF)IBA 01/2020
1	Diphosphonates (Bisphosphonates)IBA 01/2020
1	PyrrolesIBA 01/2020
1	Ligases (Synthetase)IBA 09/2019
1	Transcription Factors (Transcription Factor)IBA 09/2019
1	Oncogene Proteins (Oncogene Protein)IBA 09/2019
1	UbiquitinIBA 09/2019
1	Phenol (Carbolic Acid)FDA Link 06/2019
1	AntioxidantsIBA 06/2019
1	2,2'- azino- di- (3- ethylbenzothiazoline)- 6- sulfonic acid (ABTS)IBA 06/2019
1	LactonesIBA 06/2019
1	Alkylating AgentsIBA 01/2019
1	RNA (Ribonucleic Acid)IBA 10/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	Cytotoxins (Cytolysins)IBA 01/2018
1	pifithrinIBA 01/2018
1	Messenger RNA (mRNA)IBA 10/2017
1	GeranyltranstransferaseIBA 10/2017
1	Adenine FDA LinkGeneric 07/2017
1	Bcl-2-Like Protein 11IBA 01/2017
1	Growth Factor ReceptorsIBA 01/2017
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 01/2017
1	micaIBA 06/2015
1	4- acetoxy- 5- (1- (naphthyl))naphtho(2,3- b)pyrrolo(2,1- d)(1,4)oxazepineIBA 08/2013
1	ElementsIBA 11/2012
1	TCF Transcription FactorsIBA 11/2012
1	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2012

Therapy/Procedure

10	Therapeutics 01/2021 - 05/2006
2	Drug Therapy (Chemotherapy) 01/2020 - 01/2018
1	Radiotherapy 01/2022